Neuroknife Group — Advanced Neurosurgical Care

Athens-Based Neurosurgical Team with U.S. Training

We deliver advanced, high-acuity neurosurgical care in Greece, guided by expertise shaped at leading U.S. training institutions (Harvard Medical School, Case Western Reserve University, Medical University of South Carolina).

NEUROKNIFE • OUR MODEL

Two pillars. One uncompromising standard of safety.

Neurosurgery is not a single act. It is a sequence of high-stakes decisions: the right indication, precise planning, technical excellence, advanced expertise, and a structured postoperative course—with complete transparency and clear communication.

The Neuroknife Team

Excellence in Neurosurgery Begins with Training.

Ioannis Karampelas

Ioannis Karampelas MD FAANS

U.S. Board–Certified Neurosurgeon (ABNS)
Specialty Focus
  • Brain and skull base tumors
  • Spine surgery
  • Cerebrovascular neurosurgery
  • Neonatal and pediatric neurosurgery
  • Neuralgia surgery
U.S. Training
  • ACGME Neurosurgery Residency (Case Western Reserve University, Cleveland, OH)
  • Pediatric Neurosurgery Research Fellowship (Memorial Sloan Kettering, New York, NY)
  • Neurosurgical Oncology Fellowship (Roswell Park Cancer Center, New York, NY)
  • Diplomate, American Board of Neurological Surgery (ABNS)
Georgios Alexopoulos

Georgios Alexopoulos MD MSc

U.S. Trained (ACGME) · European Board Certified
Specialty Focus
  • Neonatal & pediatric neurosurgery
  • Brain and skull base tumors
  • Surgery for complex spinal pathology
  • Drug-resistant epilepsy
  • Peripheral nerve surgery
U.S. Training
  • ACGME Neurosurgery Residency (Saint Louis University, Saint Louis, MO)
  • Pediatric & Neonatal Neurosurgery Fellowship (Boston Children’s Hospital, Harvard Medical School, Boston, MA)
  • Specialist Certification (European Board Certification / Greece)

What We Treat

We provide specialized neurosurgical care for disorders of the brain, spine, and peripheral nerves in adults, while also delivering comprehensive expertise across the full spectrum of pediatric neurosurgery and neonatal neurosurgery.

Brain, Skull Base & Spine Tumors

Brain, Skull Base & Spine Tumors

Meningiomas, gliomas, schwannomas, pituitary tumors, and spinal tumors—managed with advanced microsurgical and endoscopic techniques, with a focus on maximal safety and optimal functional outcomes.

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Cerebrovascular Disorders of the Brain & Spinal Cord

Cerebrovascular Disorders of the Brain & Spinal Cord

Intracranial aneurysms, arteriovenous malformations (AVMs), cavernous malformations, and intracerebral hemorrhage—treated with microsurgical strategies and intraoperative ICG angiography to maximize precision and safety.

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Degenerative Spine Disorders & Deformity

Degenerative Spine Disorders & Deformity

Herniated disc, spinal stenosis, spondylolisthesis, and degenerative disease—managed with minimally invasive spine (MIS) techniques, microdiscectomy, and fusion procedures (PLIF, TLIF, MIS-TLIF). We also address spinal instability, traumatic injuries, and adult scoliosis correction, with the goal of functional restoration and accelerated recovery.

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Pediatric & Neonatal Neurosurgery

Pediatric & Neonatal Neurosurgery

Congenital brain and spine disorders, hydrocephalus, craniosynostosis, pediatric tumors, and neonatal conditions—supported by subspecialty training at a premier academic center (Harvard Medical School – Boston Children’s Hospital).

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Epilepsy & Functional Neurosurgery

Epilepsy & Functional Neurosurgery

Epilepsy surgery, invasive monitoring (SEEG), neuromodulation with DBS and VNS, and the treatment of spasticity and movement disorders through targeted, high-precision interventions.

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Traumatic Brain Injury & Spinal Trauma

Traumatic Brain Injury & Spinal Trauma

High-energy trauma, traumatic brain injury, and spinal cord injury—managed with urgent and definitive surgical care, decompression of neural structures, and spinal stabilization in accordance with international trauma protocols.

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Hydrocephalus in Adults & Children

Hydrocephalus in Adults & Children

Normal pressure hydrocephalus (NPH), congenital and acquired hydrocephalus—treated with shunt placement and programmable valves, endoscopic third ventriculostomy (ETV), and contemporary neuroendoscopic techniques, with an emphasis on long-term safety and functional improvement.

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Peripheral Nerve Disorders

Peripheral Nerve Disorders

Carpal tunnel syndrome, ulnar neuropathy, peripheral nerve disorders and tumors, brachial plexus injuries and conditions—addressed with microsurgical nerve decompression and restoration of nerve function, with the goal of pain relief and meaningful functional recovery.

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Neuralgia & Chronic Pain

Neuralgia & Chronic Pain

Trigeminal neuralgia and other cranial neuralgias, microvascular decompression (MVD), and neuromodulation with neurostimulators (SCS, PNS)—using targeted interventional techniques designed for durable relief and improved quality of life.

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Brain Surgery — Microsurgical & Endoscopic Technology

Brain Surgery — Microsurgical & Endoscopic Technology

Brain and skull base tumors, cerebrovascular disease, epilepsy, and functional neurosurgery—supported by advanced microsurgical and endoscopic platforms.

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Spine — Minimally Invasive & Complex Surgical Techniques

Spine — Minimally Invasive & Complex Surgical Techniques (MIS & Complex Spine)

MIS discectomy, spinal fusion, deformity correction, trauma care, and revision spine surgery—utilizing contemporary stabilization strategies.

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Why Choose Neuroknife Group for Your Neurosurgical Care?

U.S.-Trained Neurosurgeons in Greece

At Neuroknife Group, we unite the expertise of leading U.S. academic institutions (Harvard / Boston Children’s Hospital, Case Western Reserve, Cornell / Memorial Sloan Kettering Cancer Center, Medical University of South Carolina) with the strength and continuity of an integrated Greek neurosurgical team.

We deliver advanced, evidence-based, and minimally invasive neurosurgical care, with a consistent focus on safety, precision, and a highly individualized approach for both adults and children.

Our clinical collaborations include Athens’ leading private hospitals (HYGEIA, MITERA, Athens Medical Center), while the clinical and surgical cases of Dr. Alexopoulos are currently managed through his public-sector position at Panarkadiko General Hospital of Tripoli. Private office consultations in Athens for Dr Alexopoulos are expected to resume following May 2026.

Learn more about our team
Panarkadiko General Hospital of Tripoli Hygeia Hospital Athens Mitera Hospital Athens Athens Medical Center Pediatric Center of Athens

Residency and Advanced Fellowship Training in the United States

Experience shaped within ACGME-accredited U.S. training programs and leading academic medical centers.

International Clinical Practice

Our neurosurgeons are active in both Greece and the United States. Dr. Karampelas is board-certified and holds an academic appointment at the Medical University of South Carolina (MUSC). Dr. Alexopoulos has extensive experience in the United States and currently serves as an attending neurosurgeon at Panarkadiko General Hospital of Tripoli.

Excellence in Neurosurgical Oncology

Dr. Karampelas completed advanced fellowships at Roswell Park Comprehensive Cancer Center and Memorial Sloan Kettering Cancer Center in New York—among the world’s leading oncology institutions— with extensive experience in complex brain and skull base tumors.

Pediatric Neurosurgery at the Highest Standard

Comprehensive care across the full spectrum of pediatric and neonatal neurosurgical conditions. Dr. Alexopoulos completed advanced training at Boston Children’s Hospital, Harvard Medical School (consistently ranked the #1 pediatric hospital in the United States).

State-of-the-Art Techniques

Microsurgery with a 4K 3D digital microscope, ICG fluorescence angiography, 5-ALA fluorescence-guided tumor resection, neuroendoscopy, neuronavigation, diffusion tensor imaging (DTI) tractography, intraoperative O-arm imaging, and multimodal neuromonitoring.

Minimally Invasive Neurosurgery

Smaller incisions, reduced postoperative pain, and faster recovery through targeted, high-precision surgical techniques.

Multidisciplinary Collaboration

Close collaboration with leading ENT and vascular surgeons, with a fully integrated craniofacial and plastic surgeon as part of the team, enabling comprehensive management of complex cranial and head–neck conditions, as well as 360° spinal approaches.

Personalized Treatment Plans

Comprehensive clinical evaluation and evidence-based, individualized care tailored to each patient.


U.S. ACGME-accredited neurosurgical residency training is a global benchmark for excellence.

We are the only Greek neurosurgical group with two physicians who have undergone formal training in ACGME-accredited neurosurgery residency programs in the United States.

Personalized care & scientific precision

Our offices in Athens

A modern clinical environment designed to maintain patient privacy and support a thorough, systematic clinical assessment by delivering the highest academic standards that define our philosophy in Neuroknife.

Neuroknife clinic in Marousi — modern medical office for comprehensive evaluation
Designed for a personalized, human experience. Calm structure, and an environment that supports thoughtful, evidence-based clinical decision-making.

Why does the environment matter?

In neurosurgery, trust begins long before any intervention. We prioritize clear communication and complete transparency in every aspect of clinical decision-making.

  • Privacy: a quiet setting for discussing confidential patient information and sensitive therapeutic plans.
  • Organization: a structured workflow for evaluation, imaging review, and individualized treatment planning.
  • Academic consistency: spaces that reflect the standards of training, rigor, and the clinical culture of Neuroknife.

Contact

We are here to support you—whether you are scheduling an appointment, requesting a telemedicine consultation, seeking a second opinion, or coordinating hospitalization.

Neuroknife Clinic

6–8 Ippokratous St, Ground Floor
151 23, Marousi, Athens

Phone Numbers

Clinic: 6936 933 042
Mobile: 6974 574 625
U.S. (international patients): +1 917 797 1363
WhatsApp: +30 693 693 3042

Office Hours

Monday – Friday, 09:00 – 17:00

Saturday, 09:00 – 13:00 (by appointment)

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